The three Premier League and three La Liga clubs in the last eight avoided each other, with Manchester City up against Atletico Madrid and Liverpool to face Portuguese side Benfica.
In other ties, Serie A champions Juventus face Europa League winners Atletico Madrid and Barcelona take on Olympique Lyonnais.
Visitors Ajax had looked comfortable after former Southampton winger Tadic set up the first goal with a swerving cross before drilling home the second himself.
Napoli qualified for the Champions League group stage by winning 3-0 at Bologna on Wednesday and two goals from Mario Balotelli kept AC Milan on course for the qualifying round with a 4-0 victory at Pescara.
From Royal Challengers Bengaluru's historic first IPL title to star javelin thrower Neeraj Chopra finally breaking the iconic 90-meter mark to India women winning their first cricket World Cup, this was the year of long-awaited victories and record-breaking feats.
A summary of Wednesday's action in the UEFA Champions League.
United are unbeaten in all competitions since Solskjaer replaced Jose Mourinho in December and their improvement is down to the Norwegian's insistence on an attacking style of play, as opposed to the defensive fare served up by his predecessor.
Manchester City suffered from deja vu as Luis Suarez's double gave Barcelona a 2-1 first leg lead in a Champions League last 16 tie at the Etihad although Lionel Messi's late penalty miss left the door ajar on Tuesday.
Teenager Curtis Jones grabbed a 58th-minute winner as an injury-hit Liverpool qualified for the knockout stage of the Champions League with a 1-0 win over Ajax Amsterdam at Anfield on Tuesday.
The 38-year-old defender became only the fifth player, and first Italian, to notch up 100 Champions League appearances.
AIFF asks clubs to confirm participation in delayed ISL
A complete round-up of the weekend action in the main European leagues.
Manchester City came out on top in an epic Champions League battle against Monaco whereasAtletico Madrid beat hosts Bayer Leverkusen 4-2 in a topsy-turvy encounter.
In the day's other fixtures, Croatian champions Dinamo Zagreb took a big step towards the next stage with a 2-0 win at Georgians Saburtalo and Copenhagen won at Welsh side The New Saints by the same score.
Arsenal will have to produce the biggest second leg comeback in a Champions League knockout tie to avoid a seventh successive exit at the last 16 stage when they host Bayern Munich on Tuesday.
If SRH's batting unit fires consistently and the bowlers find rhythm, they have the potential to challenge for the playoffs.
There will be plenty of tension in the air in North London on Wednesday when out-of-sorts Arsenal face Borussia Dortmund seeking to qualify from the Champions League group stage for the 15th successive season.
Juventus did the bare minimum as they scraped into the Champions League knockout stage on Tuesday with a 0-0 draw at home to Atletico Madrid, a result which also suited the Spaniards who topped the group.
It was a dramatic night at the Champions League as Barcelona's Anssumane Fati -- 17 years and 40 days old - became the youngest to net a goal in the competition. Last season's semi-finalists, Ajax were eliminated by Valencia while Napoli's coach Ancelotti was shown the door despite the team's progress. Here are Images from the Champions League matches played on Tuesday
Liverpool laboured to a 2-0 win over Denmark's Midtjylland on Tuesday as a goal from Diogo Jota and a Mohamed Salah penalty secured a hard-fought Champions League Group D victory at Anfield.
Billionaire David Blitzer, co-founder of Harris Blitzer Sports & Entertainment, is conducting due diligence on Royal Challengers Bengaluru and Rajasthan Royals.
FC Goa on became the first team from the country to secure a berth in the group stage of the AFC Champions League, the continent's top-tier club competition, after beating Jamshedpur FC 5-0 in an Indian Super League match, in Jamshedpur, on Wednesday.
The West Indies and Zimbabwe, both undefeated in the first round, will clash in a crucial T20 World Cup Super Eight match. The West Indies' power-hitting prowess will be tested against Zimbabwe's resilience and all-round strength.
Olympiakos Piraeus battled back from a two-goal deficit to earn a 2-2 home draw with last year's runners-up Tottenham Hotspur in their Champions League Group B opener.
Spain became the first country to have five teams in the Champions League group stage in one season after Valencia squeezed past Monaco .
The Arsenal captain is a doubt for the match against Celta Vigo after injuring his knee on Saturday.
Liverpool were beaten 1-0 away to Atletico Madrid in their last-16 first leg on Tuesday.
Perennial finalists Delhi Capitals take on in-form Gujarat Giants in the WPL eliminator, with a spot in the February 5 final at stake.
Needing victory over last year's runners-up, Basel battled to a 2-1 win to jump ahead of United into second place in Group C and send the English champions into the Europa League. City, running riot at the top of the Premier League, beat already-qualified Bayern Munich 2-0 in their final Group A match but it proved in vain for the competition's newcomers as Napoli won 2-0 at Villarreal to grab second place.
Chelsea rounded off the UEFA Champions League group stage with a 3-1 victory over Sporting.
Inter, Liverpool sweating on last-16 spots
Former European Cup winners Celtic and Ajax Amsterdam safely negotiated tricky Champions League third-round qualifying ties on Wednesday to move one step away from the lucrative group stage.
Ahead of the UEFA Champions League proper, which kicks-off next month, Bikash Mohapatra/Rediff.com tells football fans what to expect in this year's competition.
Bayer Leverkusen have sacked manager Erik ten Hag after two league games in charge, the Bundesliga club said on Monday, with the weekend draw at Werder Bremen not enough to save the Dutchman's job.
The draw was made on Monday for the Champions League round of 16.
European soccer's governing body has so far resisted implementation of the VAR system, which allows key incidents to be reviewed with the use of video replays and was used at the World Cup in Russia this year.
Mohun Bagan Super Giant vs East Bengal ISL derby on May 3 as per tentative schedule
Swedish club AIK have been fined for crowd trouble at their Champions League qualifying tie at home to Norway's Rosenborg Trondheim last week, European soccer's governing body UEFA said Tuesday.
Manchester City's Erling Haaland came back to haunt Borussia Dortmund with a clinical finish against his former team, while Phil Foden bagged a brilliant brace as the hosts cruised to a 4-1 win in the Champions League on Wednesday to climb to fourth.
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